Located in the pancreas, the pancreatic vein is responsible for draining the pancreas into the superior mesenteric and splenic veins.

It contributes to the significant role of the pancreas since this gland has a diverse set of functions in digestion and sugar metabolism. The pancreas also serves as a storage reservoir for several digestive enzymes.

The pancreatic vein is connected to several small veins that drain the body and tail sections of the pancreas.