Is coffee a colonic stimulant?
- PMID: 9581985
- DOI: 10.1097/00042737-199802000-00003
Is coffee a colonic stimulant?
Abstract
Background: It is unclear if ingestion of coffee affects colonic function and if this effect is due to its caffeine content. We investigated the effects of coffee on colonic motor activity in healthy humans.
Methods: We performed ambulatory colonic manometry by placing a six-sensor solid-state probe up to the mid-transverse colon in 12 healthy subjects. The following day, over a 10 h period, subjects received four stimuli: 240 ml of three drinks at 45 degrees C in random order: black Colombian coffee (150 mg caffeine), decaffeinated coffee or water and 1000 kcal meal. We analyzed the effects of each stimulant on colonic motor responses.
Results: Caffeinated coffee, decaffeinated coffee and meal induced more activity in the colon with a greater area under the curve of pressure waves (P < 0.01) and a greater number of propagated contractions (P < 0.05) when compared with water. Caffeinated coffee, decaffeinated coffee and meal induced greater (P < 0.05) motor activity in the transverse/descending colon when compared with the rectosigmoid colon. The effects of decaffeinated coffee on colonic motility were not significantly different from those of water or caffeinated coffee and were lower (P < 0.05) than that of a meal.
Conclusion: Caffeinated coffee stimulates colonic motor activity. Its magnitude is similar to a meal, 60% stronger than water and 23% stronger than decaffeinated coffee.
Cited by 18 articles
-
Dietary Patterns Associated to Clinical Aspects in Crohn's Disease Patients.Sci Rep. 2020 Apr 27;10(1):7033. doi: 10.1038/s41598-020-64024-1. Sci Rep. 2020. PMID: 32341416 Free PMC article.
-
Current perspectives on the diagnosis and management of functional anorectal disorders in patients with inflammatory bowel disease.Therap Adv Gastroenterol. 2018 Dec 6;11:1756284818816956. doi: 10.1177/1756284818816956. eCollection 2018. Therap Adv Gastroenterol. 2018. PMID: 30574193 Free PMC article. Review.
-
Effect of postoperative coffee consumption on gastrointestinal function after abdominal surgery: A systematic review and meta-analysis of randomized controlled trials.Sci Rep. 2018 Nov 26;8(1):17349. doi: 10.1038/s41598-018-35752-2. Sci Rep. 2018. PMID: 30478433 Free PMC article.
-
Longer colonic transit time is associated with laxative and drug use, lifestyle factors, and symptoms of constipation.Acta Radiol Open. 2018 Oct 22;7(10):2058460118807232. doi: 10.1177/2058460118807232. eCollection 2018 Sep. Acta Radiol Open. 2018. PMID: 30364803 Free PMC article.
-
Diet in irritable bowel syndrome: What to recommend, not what to forbid to patients!World J Gastroenterol. 2017 Jun 7;23(21):3771-3783. doi: 10.3748/wjg.v23.i21.3771. World J Gastroenterol. 2017. PMID: 28638217 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grant support
LinkOut - more resources
-
Full Text Sources
-
Other Literature Sources
-
Medical