Inclusion of Atlantic salmon in the Chinese diet reduces cardiovascular disease risk markers in dyslipidemic adult men
- PMID: 20797476
- DOI: 10.1016/j.nutres.2010.06.010
Inclusion of Atlantic salmon in the Chinese diet reduces cardiovascular disease risk markers in dyslipidemic adult men
Abstract
Although the beneficial effects of n-3 fatty acids on several physiologic functions have been widely reported, information about the effects of oily fish in the Asian diet on cardiovascular disease (CVD) risk is diminutive. We hypothesize that daily inclusion of oily fish for 8 weeks in the Chinese diet will elevate serum eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) levels and reduce CVD risk markers in dyslipidemic adult men, comparable with the effects generally observed by inclusion of oily fish in the Western diet. In this 8-week randomized, parallel-arm, food-based intervention study, lunches were prepared with 500 g pork/chicken/beef, typically consumed fish (hairtail and freshwater carp), or oily fish (salmon). Male subjects aged between 35 and 70 years with hyperlipidemia were randomly assigned to eat lunches with pork/chicken/beef (n = 30 subjects at 8 weeks), freshwater fish (n = 30), or oily fish (n = 32). Circulating markers were measured at baseline and at 8 weeks. In the oily fish diet, dietary EPA and DHA levels were significantly increased as compared with other diets; and the n-6:n-3 polyunsaturated fatty acid ratio was decreased (P < .05). Thus, the oily fish diet significantly elevated serum EPA and DHA concentrations (P < .01) and lowered serum n-6:n-3 ratio at 8 weeks (P < .05). Furthermore, oily fish intake significantly reduced serum levels of triglycerides (P < .05) and interleukin-6 (P < .01) and increased levels of high-density lipoprotein cholesterol (P < .01). In conclusion, daily inclusion of oily fish as part of the Chinese diet for 8 weeks is sufficient to significantly increase the serum content of long-chain n-3 polyunsaturated fatty acids and reduce levels of CVD risk markers in dyslipidemic adult men.
Copyright 2010 Elsevier Inc. All rights reserved.
Similar articles
-
Dietary inclusion of salmon, herring and pompano as oily fish reduces CVD risk markers in dyslipidaemic middle-aged and elderly Chinese women.Br J Nutr. 2012 Oct 28;108(8):1455-65. doi: 10.1017/S0007114511006866. Epub 2012 Jan 6. Br J Nutr. 2012. PMID: 22221492 Clinical Trial.
-
Effects of alpha-linolenic acid versus those of EPA/DHA on cardiovascular risk markers in healthy elderly subjects.Eur J Clin Nutr. 2006 Aug;60(8):978-84. doi: 10.1038/sj.ejcn.1602408. Epub 2006 Feb 15. Eur J Clin Nutr. 2006. PMID: 16482073 Clinical Trial.
-
Supplementation with fish oil affects the association between very long-chain n-3 polyunsaturated fatty acids in serum non-esterified fatty acids and soluble vascular cell adhesion molecule-1.Clin Sci (Lond). 2003 Jul;105(1):13-20. doi: 10.1042/CS20020349. Clin Sci (Lond). 2003. PMID: 12589702 Clinical Trial.
-
Risk stratification by the "EPA+DHA level" and the "EPA/AA ratio" focus on anti-inflammatory and antiarrhythmogenic effects of long-chain omega-3 fatty acids.Herz. 2004 Nov;29(7):673-85. doi: 10.1007/s00059-004-2602-4. Herz. 2004. PMID: 15580322 Review.
-
Docosahexaenoic acid (DHA) and cardiovascular disease risk factors.Prostaglandins Leukot Essent Fatty Acids. 2009 Aug-Sep;81(2-3):199-204. doi: 10.1016/j.plefa.2009.05.016. Epub 2009 Jul 9. Prostaglandins Leukot Essent Fatty Acids. 2009. PMID: 19545988 Review.
Cited by 9 articles
-
Biomarkers of meat and seafood intake: an extensive literature review.Genes Nutr. 2019 Dec 30;14:35. doi: 10.1186/s12263-019-0656-4. eCollection 2019. Genes Nutr. 2019. PMID: 31908682 Free PMC article. Review.
-
Oily Fish Consumption and the Risk of Dyslipidemia in Korean Adults: A Prospective Cohort Study Based on the Health Examinees Gem (HEXA-G) Study.Nutrients. 2019 Oct 17;11(10):2506. doi: 10.3390/nu11102506. Nutrients. 2019. PMID: 31627478 Free PMC article.
-
Structural Elucidation of Irish Organic Farmed Salmon (Salmo salar) Polar Lipids with Antithrombotic Activities.Mar Drugs. 2018 May 23;16(6):176. doi: 10.3390/md16060176. Mar Drugs. 2018. PMID: 29882848 Free PMC article.
-
Effects of baked and raw salmon fillet on lipids and n-3 PUFAs in serum and tissues in Zucker fa/fa rats.Food Nutr Res. 2017 Jun 12;61(1):1333395. doi: 10.1080/16546628.2017.1333395. eCollection 2017. Food Nutr Res. 2017. PMID: 28659746 Free PMC article.
-
ω-3 Fatty Acids and Cardiovascular Diseases: Effects, Mechanisms and Dietary Relevance.Int J Mol Sci. 2015 Sep 18;16(9):22636-61. doi: 10.3390/ijms160922636. Int J Mol Sci. 2015. PMID: 26393581 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
-
Full Text Sources
-
Other Literature Sources
-
Research Materials