Potential health benefits of broccoli- a chemico-biological overview
- PMID: 19519500
- DOI: 10.2174/138955709788452685
Potential health benefits of broccoli- a chemico-biological overview
Abstract
The concept that bioactive components in functional foods are efficacious for the improvement of health, has recently gained much importance. The cruciferous vegetables which include broccoli, cabbage and cauliflower are excellent source of phytochemicals including glucosinolates and their byproducts, phenolics and antioxidant vitamins as well as dietary minerals. Broccoli consumption mediates a variety of functions including providing antioxidants, regulating enzymes and controlling apoptosis and cell cycle. The organosulfur chemicals namely glucosinolates and the S-methyl cysteine sulphoxide found in broccoli in concert with other constituents such as vitamins E, C, K and the minerals such as iron, zinc, selenium and the polyphenols namely kaempferol, quercetin glucosides and isorhamnetin are presumably responsible for various health benefits of broccoli. There exists no comprehensive review on the health promoting effects of phytochemical compounds present in broccoli so far. This review compiles the evidence for the beneficial role of glucosinolates in conjugation with the other phytoconstituents for human health. It also gives an overview on the chemical and biological characterization of potential bioactive compounds of broccoli including the interaction of phytoconstituents on its bioactivity. Further, the molecular basis of the biological activities of the chemicals present in broccoli potentially responsible for health promotion, from chemoprevention to cardio protection, are outlined based on in vitro and in vivo studies with a note on the structure activity relationship of sulforaphane and a few other isothiocyanates.
Similar articles
-
Cultivation conditions and selenium fertilization alter the phenolic profile, glucosinolate, and sulforaphane content of broccoli.J Med Food. 2005 Summer;8(2):204-14. doi: 10.1089/jmf.2005.8.204. J Med Food. 2005. PMID: 16117613
-
Extraction, chemical characterization and biological activity determination of broccoli health promoting compounds.J Chromatogr A. 2013 Oct 25;1313:78-95. doi: 10.1016/j.chroma.2013.07.051. Epub 2013 Jul 16. J Chromatogr A. 2013. PMID: 23899380 Review.
-
Phytochemical composition and biological activities of differently pigmented cabbage (Brassica oleracea var. capitata) and cauliflower (Brassica oleracea var. botrytis) varieties.J Sci Food Agric. 2019 Sep;99(12):5499-5507. doi: 10.1002/jsfa.9811. Epub 2019 Jun 17. J Sci Food Agric. 2019. PMID: 31099412
-
Bioactive organosulfur phytochemicals in Brassica oleracea vegetables--a review.Food Chem Toxicol. 1995 Jun;33(6):537-43. doi: 10.1016/0278-6915(95)00017-v. Food Chem Toxicol. 1995. PMID: 7797181 Review.
-
Chemical and biological characterisation of nutraceutical compounds of broccoli.J Pharm Biomed Anal. 2006 Aug 28;41(5):1508-22. doi: 10.1016/j.jpba.2006.04.003. Epub 2006 May 19. J Pharm Biomed Anal. 2006. PMID: 16713696 Review.
Cited by 13 articles
-
Side Streams of Broccoli Leaves: A Climate Smart and Healthy Food Ingredient.Int J Environ Res Public Health. 2020 Apr 1;17(7):2406. doi: 10.3390/ijerph17072406. Int J Environ Res Public Health. 2020. PMID: 32244813 Free PMC article.
-
Concentration-dependent effects of tungstate on germination, growth, lignification-related enzymes, antioxidants, and reactive oxygen species in broccoli (Brassica oleracea var. italica L.).Environ Sci Pollut Res Int. 2019 Dec;26(36):36441-36457. doi: 10.1007/s11356-019-06603-y. Epub 2019 Nov 14. Environ Sci Pollut Res Int. 2019. PMID: 31728946
-
Are (All) Consumers Averse to Bitter Taste?Nutrients. 2019 Feb 2;11(2):323. doi: 10.3390/nu11020323. Nutrients. 2019. PMID: 30717365 Free PMC article. Clinical Trial.
-
Salivary proteins alter taste-guided behaviors and taste nerve signaling in rat.Physiol Behav. 2018 Feb 1;184:150-161. doi: 10.1016/j.physbeh.2017.11.021. Epub 2017 Nov 21. Physiol Behav. 2018. PMID: 29162505 Free PMC article.
-
Selenium-Induced Toxicity Is Counteracted by Sulfur in Broccoli (Brassica oleracea L. var. italica).Front Plant Sci. 2017 Aug 18;8:1425. doi: 10.3389/fpls.2017.01425. eCollection 2017. Front Plant Sci. 2017. PMID: 28868057 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
-
Full Text Sources
-
Other Literature Sources