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. 1991 Jun;45(6):299-307.

Urinary riboflavin and its metabolites: effects of riboflavin supplementation in healthy residents of rural Georgia (USA)

Z K Roughead  1 , D B McCormick
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  • PMID: 1915203

Urinary riboflavin and its metabolites: effects of riboflavin supplementation in healthy residents of rural Georgia (USA)

Z K Roughead et al. Eur J Clin Nutr. .
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Abstract

The following study was designed to provide a comprehensive assessment of urinary riboflavin and flavin metabolites before and after ingestion of a riboflavin load in normal human volunteers. With respect to riboflavin, the total flavin excretion, the flavin-to-creatinine ratio, and the response of the flavin catabolites to the supplement indicate a well-nourished population. Differences in the effects of supplementation on the specific flavin catabolites across sex and age groups are included in detail for the first time. The feasibility of the use of flavin catabolites for determination of riboflavin status should be tested further in individuals with clinical signs of ariboflavinosis.

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    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), Turck D, Bresson JL, Burlingame B, Dean T, Fairweather-Tait S, Heinonen M, Hirsch-Ernst KI, Mangelsdorf I, McArdle HJ, Naska A, Nowicka G, Pentieva K, Sanz Y, Siani A, Sjödin A, Stern M, Tomé D, Van Loveren H, Vinceti M, Willatts P, Lamberg-Allardt C, Przyrembel H, Tetens I, Dumas C, Fabiani L, Forss AC, Ioannidou S, Neuhäuser-Berthold M. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), et al. EFSA J. 2017 Aug 7;15(8):e04919. doi: 10.2903/j.efsa.2017.4919. eCollection 2017 Aug. EFSA J. 2017. PMID: 32625611 Free PMC article.

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