Review
doi: 10.1111/j.1753-4887.2000.tb01827.x.
Diuretics and vitamin B1: are diuretics a risk factor for thiamin malnutrition?
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- PMID: 11127971
- DOI: 10.1111/j.1753-4887.2000.tb01827.x
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Review
Diuretics and vitamin B1: are diuretics a risk factor for thiamin malnutrition?
Nutr Rev.
.
Free article
Abstract
Despite modern pharmacologic agents in the therapy of heart failure, the prevalence of heart failure is increasing worldwide. In the vitamin B1 deficiency disease beriberi, cardiac symptoms may represent the central feature. Two new studies confirmed that all diuretics lead to increased urinary thiamin excretion depending on the urinary flow rate. In a subject at risk, such as an elderly patient, chronic diuretic treatment may lead to a subclinical thiamin deficiency. Whether subclinical thiamin nutriture is a modulator of the prevalence and/or severity of heart failure is not known; however, it seems to be plausible from the metabolic point of view.
Comment in
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How prevalent is thiamin deficiency in heart failure patients?Nutr Rev. 2001 Oct;59(10):342-4. doi: 10.1111/j.1753-4887.2001.tb06960.x. Nutr Rev. 2001. PMID: 11669241 No abstract available.
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